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From Stanford University. Neil Hall is an assistant investigator at the Institute for Genomic Research. S. D. in molecular biology from the University of Liverpool. Before joining the institute, he was a project manager in bioinformatics at the Sanger Institute. His major research is on the genomics of infectious diseases, using bioinformatics analysis to elucidate the evolution of pathogenic organisms, how they respond to selective forces acting upon them, and how the ability to infect humans originates.

Halanych. 2003. DNA, PCR and formalinized animal tissue—A short review and protocols. Organisms, Diversity and Evolution 3(3):195-205. G. W. Pietsch, and P. Bentzen. 1997. Enhanced DNA extraction and PCR amplification of mitochondrial genes from formalin-fixed museum specimens. Biotechniques 22:394-396. , M. V. Joyner, P. S. B. Jones, and S. Ellard. 2001. Longe PCR products from paraffin-embedded tissue. Qiagen News 3:15-17. R. M. Crothers. 1998. Characterization of covalent adriamycin DNA adducts.

High throughput The rapid (and simultaneous) processing of large sample sets. Microarrays A microscope slide or other solid support on which many distinct complementary DNA or DNA oligo­ nucleotides are patterned at high density in an ­addressable array. Microarrays are interrogated by hybridization to fluorescently labeled complementary DNA or RNA to identify actively transcribed genes. Mutagenesis The development of a mutation. PCR Polymerase chain reaction; a fast and inexpensive technique for amplifying a piece of DNA.

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