By M. Klaus, et al.,
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Extra info for Care of the high-risk neonate
3. 4. 5. The application of current technology thus provides the clinical team with the means of minimizing both fetal death in utero and preventable neonatal morbidity and mortality from the hazards of prematurity. Together with intensive control of maternal blood glucose, the technology of fetal surveillance offers the possibility of normalizing perinatal outcomes in large numbers of diabetic pregnancies. 6. ": 167 Major obstetric complications resulting in delivery of very lowbirth-weight infants include premature rupture of membranes (PROM) (75%), premature labor (45%), multiple gestation (16%), amnionitis (14%), and premature separation of the placenta (7%).
167 Major obstetric complications resulting in delivery of very lowbirth-weight infants include premature rupture of membranes (PROM) (75%), premature labor (45%), multiple gestation (16%), amnionitis (14%), and premature separation of the placenta (7%). The rationale for a group of specific obstetric interventions directed at optimizing the outcome of low-birth-weight infants currently exists and is illustrated in the following section. The following basic principles apply: 1. Prevent prematurity through maximal an- tenatal care, avoidance of unnecessary 7.
Earlyclinical trials and a meta-analysis suggested that low-dose aspirin prevented preeclampsia without harming the mother or fetus. Caritis et al randomly treated a high-risk group of women (pregestational, insulin-dependent diabetes, chronic hypertension, multiple gestations, or previous preeclampsia) with 60 mg of aspirin a day or placebo between the 13th and 26th week of pregnancy. They were unable to reduce the incidence of preeclampsia, but did find a trend toward a reduction in preterm deliveries and perinatal deaths among the aspirin-treated group.